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Imec, the world's leading research and innovation hub in nanoelectronics and digital technology, and miDiagnostics, a spin-off of imec in collaboration with Johns Hopkins University specialized in the development of point-of-care tests for screening, diagnosing and monitoring a wide range of health conditions, announce that they have signed a non-exclusive licensing agreement for imec’s patented technology whereby aerosols and droplets from exhaled breath are captured for screening for viral RNA through miDiagnostics ultrafast PCR technology. The agreement enables miDiagnostics to kickstart the commercialization of a COVID-19 breathalyzer (as opposed to classical COVID-19 testing methods based on blood, saliva or a sample from the nose/throat cavity).
In the past year, imec developed a breath sampler based on imec’s unique chip technology, and performed clinical studies with the university hospital and university of Leuven showing that imec’s breath sampler is capable of capturing the SARS-CoV-2 virus in exhaled air, and detecting the viral RNA quickly and reliably. Also, imec developed a sampling instrument integrating the breath sampling technology and imec’s ultra-fast PCR-test, and optimized the robustness and ease of use, to achieve a functioning proof-of-concept to date.
"I note with great pride that we have run an impressive course in the past months," says Luc Van den hove, CEO at imec. "We have succeeded in transforming a promising concept and groundbreaking technology into a functional proof-of-concept that has passed both user tests and clinical studies. This is the first time that we have gone this far in the development of our chip technology towards commercialization. With this proof-of-concept, we can demonstrate -much closer to the market- the added value of our technology, while significantly reducing the time-to-market for our partners. The license agreement with miDiagnostics is an important milestone for imec: our breakthrough technology will help curb the COVID-19 pandemic in the foreseeable future."
As COVID-19 will certainly not be the last virus to engulf the world, imec is already looking further, by investigating how its patented technology can also be applied to diagnose other infectious airborne diseases. In addition, imec is also looking into its application in diagnosing diseases such as cancer. Interested companies are welcome to join this effort.
“Despite the vaccination campaigns, there’s still a great need for accessible and reliable rapid tests to curb new virus outbreaks or to avoid unnecessary quarantine. With our license to imec's groundbreaking technology, we aim to make our ultra-fast PCR technology, which we now use for nasal swabs, also compatible with exhaled air - the perfect sample for silicon-based PCR. This first prototype will be tested at the airport in November in collaboration with Brussels Airport, Ecolog and Eurofins,” says Katleen Verleysen, CEO of miDiagnostics.
“Our research investments through imec lead to new technological breakthroughs. The interplay between knowledge, research and entrepreneurship provides economic and social added value. With the new breathalyzer, we are also making history in testing COVID-19. The development of these tests is of great importance for public health. In this way we will be able to manage this pandemic even better and increase the comfort for people who need to be tested. That is why I am proud that we have been able to support the development and research of imec,” says Flemish Minister of Innovation Hilde Crevits.
About imec
Imec (imec-int.com) is a world-leading research and innovation center in nanoelectronics and digital technologies. Imec leverages its state-of-the-art R&D infrastructure and its team of more than 5,000 employees and top researchers, for R&D in advanced semiconductor and system scaling, silicon photonics, artificial intelligence, beyond 5G communications and sensing technologies, and in application domains such as health and life sciences, mobility, industry 4.0, agrofood, smart cities, sustainable energy, education, … Imec unites world-industry leaders across the semiconductor value chain, Flanders-based and international tech, pharma, medical and ICT companies, start-ups, and academia and knowledge centers. Imec is headquartered in Leuven (Belgium), and has research sites across Belgium, in the Netherlands, Taiwan and the USA, and offices in China, India and Japan. In 2020, imec's revenue (P&L) totaled 680 million euro.
Imec is a registered trademark for the activities of imec International (IMEC International, a legal entity set up under Belgian law as a “stichting van openbaar nut”), imec Belgium (IMEC vzw supported by the Flemish Government), imec the Netherlands (Stichting IMEC Nederland), imec Taiwan (IMEC Taiwan Co.), imec China (IMEC Microelectronics (Shanghai) Co. Ltd.), imec India (IMEC India Private Limited), imec San Francisco (IMEC Inc.) and imec Florida (IMEC USA Nanoelectronics Design Center Inc.).
About miDiagnostics
miDiagnostics (midiagnostics.com) is using silicon chip technology which will bring miniaturized, rapid, easy-to-use, lab-quality tests direct to the patient and clinician. Combining a nanofluidic processor on a chip and a compact reader, miDiagnostics can measure virtually any biomarker from a minimally invasive sample such as drops of fingerprick blood or swabs. The Company is developing an extensive portfolio of tests for screening, diagnosis and monitoring of a wide range of health conditions, including infectious diseases. Spun out of the world-leading R&D and innovation hub in nanoelectronics and digital technologies, imec, and a research collaboration with Johns Hopkins University, the leading US research and medical centre, miDiagnostics’ goal is to enable fast, comprehensive and cost-effective health analysis, regardless of location. Based in Leuven, Belgium, miDiagnostics is a privately held company created in 2015.
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