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Fabricating Highly Mono-disperse Nanospheres with Biomulecules - A new research report coming out of China shows that highly monodispersed nanospheres of cystine (a sulfur-containing amino acid) aggregate were successfully produced by a quite simple method without the assistance of any other inorganic materials.
Fabricating Highly Mono-disperse Nanospheres with Biomulecules

 

NewswireToday - /newswire/ - Honolulu, HI, United States, 2006/10/17 - A new research report coming out of China shows that highly monodispersed nanospheres of cystine (a sulfur-containing amino acid) aggregate were successfully produced by a quite simple method without the assistance of any other inorganic materials..

   
 
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Controlling the shape of nanostructures is one of the challenging issues presently faced by synthetic chemists and materials engineers. Various shapes of nanomaterials, such as sphere-, rod-, wire-, triangle-, cube-, and tube-outlines have been synthesized by various approaches. However, to produce nanostructures with high monodispersity is still one of the major issues to be solved. Most work in this area focused on inorganic or synthetically organic materials. Using pure biomolecules to produce nano- or micro-structures, without the assistance of inorganic materials, is rare.

Biocompatible nanospheres have been and remain of intense interest for biosensor, drug delivery, and biomedical contrast imaging. A new research report coming out of China now shows that highly monodispersed nanospheres of cystine (a sulfur-containing amino acid) aggregate were successfully produced by a quite simple method without the assistance of any other inorganic materials. This work could be of great significance in the production of nanomaterials, biosensors, and drug delivery.

Professor Zhanfang Ma from the Chemistry Department at Northeast Normal University in Chanchun, PR China, explains his group's recent findings to Nanowerk; "Amino acid molecules are one of the most important candidates to fabricate nanomaterials due to their stability, cost-saving, nontoxicity, and biocompatibility. Herein, we prepared multiple shapes of nano- and micro-structured cystine aggregates only by adjusting the concentration and pH value of the L-Cysteine solution under ultrasonic irradiation."

Importantly, as Ma points out, a large amount of highly monodispersed nanospheres of cystine aggregates 225 nm in diameter without any other shapes were easily obtained.

"To the best of our knowledge, this is the first time highly monodispersed nanospheres have been prepared using a common amino acid with small molecular weight" he says. "The reported method will promote new possibilities for future applications in biosensor, drug delivery, and medicine."

The new findings were reported in a paper, titled "A facile method to produce highly monodispersed nanospheres of cystine aggregates", published in the September 28, 2006 online edition of Nanotechnology.

Read the full article on the Nanowerk website.

About Nanowerk

Nanowerk is a leading nanotechnology information portal. Apart from its unique Nanomaterial Database™, with over 1,300 products from 90 suppliers, it provides the most complete nanotech events calendar; hundreds of links to universities, labs, researchers, associations, networks and international initiatives involved in nanotechnology; daily news; downloadable reports; and much more. The site includes a daily “Spotlight” section featuring Nanowerk-exclusive reviews and summaries of cutting-edge nanotechnology research by guest authors and Nanowerk editors. Nanowerk also publishes the nanoRISK newsletter – a constructive contribution to the debate about the potential risks of nanotechnology.

By Michael Berger, Copyright 2006 Nanowerk LLC

 
 
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Fabricating Highly Mono-disperse Nanospheres with Biomulecules

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Publisher Contact: Michael Berger - Nanowerk.com 
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