NewswireToday - /newswire/ -
Fremont, CA, United States, 2011/04/19 - AnaSpec, Eurogentec Group is pleased to release the following dipeptides, the majority of which are >95% pure.
Dipeptide and tripeptide libraries can be systematically constructed to contain almost all possible combinations of the 20 common amino acids.1 Peptide libraries can be used in the study of ligand-receptor interactions, epitope mapping, vaccine development, and drug screening.2 Dipeptide libraries, in particular, can be prepared at relatively low cost to span a broad range of physicochemical properties, making them especially useful to pharmaceutical companies as a potential source for novel drug structures.3 Another advantage of dipeptide libraries is their simple structure, which eliminates the need for deconvolution in identifying novel structures and allows the peptides to be taken up by bacterial and eukaryotic cell membranes for direct interaction with target proteins in vivo.3-6
1. Xiang, D. et al. Biochem 48, 4567 (2009).
2. Liu, R. et al. Exp Hematol 31, 11 (2003).
3. Xie, J. et al. J Med Chem 52, 3516 (2009).
4. Boden, P. et al. J Med Chem 39, 1664 (1996).
5. Olson, E. et al. J Bacteriol 173, 234 (1991).
6. Saito, H. et al. Am J Physiol 265, 289 (1993).
AnaSpec, Eurogentec Group
AnaSpec (anaspec.com), Eurogentec Group is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, amino acids, oligonucleotides, and qPCRs. AnaSpec carries a broad product line of biochemicals and reagents for basic research, high-throughput screening and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development, fluorescent dyes, and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008.