NewswireToday - /newswire/ -
Fremont, CA, United States, 2011/04/11 - AnaSpec, Eurogentec Group is pleased to be the first in the industry to establish a new product line of zebrafish specific (Z-Fish™) antibodies to support the increasing needs of researchers.
In collaboration with the University of Utah, Salt Lake City, Utah, AnaSpec's Z-Fish™ polyclonal anti-lysozyme was found to completely overlap with mpo: GFP labeled neutrophils. This indicates that lysozyme is a neutrophil marker in zebrafish. Lysozyme C (lyz), a cationic glycoside hydrolase, breaks down N-acetyl muramic b-1, 4 N-acetyl glucosamine linkages in the bacterial cell wall.1-2 In zebrafish, this enzyme is expressed exclusively in myeloid cells, 2 and is used for hematopoietic developmental studies in zebrafish. This antibody was raised using a synthetic peptide derived from the intermediate region of zebrafish lysozyme protein (GenBank accession # NP_631919.1).
Our expanding list of Z-Fish™ antibodies includes targets used in transcriptional regulation, signal transduction, apoptosis and autophagy, cell cycle control, cytoskeleton, glucose and energy metabolism, and immunity research. Antibodies were verified in ELISA. Many were verified in western blots using zebrafish lysates. As well, these Z-Fish™ antibodies are predicted to work in IHC, many of which have good IHC results. Antibodies are supplied in 150 ul size, this amount is enough for 15 mini gels.
1. Gordon, S. et al. J Exp Med 139(5), 1228 (1974).
2. Kitaguchi, T. et al. Mech Dev 126, 314 (2009).
AnaSpec, Eurogentec Group
AnaSpec, Eurogentec Group (anaspec.com) is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, amino acids, oligonucleotides, and qPCRs. AnaSpec carries a broad product line of biochemicals and reagents for basic research, high-throughput screening and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development, fluorescent dyes, and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008.