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Fremont, CA, United States, 2011/02/03 - AnaSpec, Eurogentec Group, is pleased to highlight our wide collection of Fmoc- and Boc-protected PEGylated amino acids for PEGylated peptides synthesis.
PEGylation has become a well-accepted method for the delivery of biopharmaceuticals-especially peptide and protein drugs.1-4 Simple modification of a drug with polyethylene glycol (PEG) not only is capable of improving the drug’s solubility, diminishing the potential for aggregation, and minimizing interference for both in vitro and in vivo applications, but is also able to protect it from proteolytic digestion, increasing its half-life in biological applications in the process.1-4 Custom synthesis of PEGylated peptides is available through AnaSpec’s Fremont, California facilities.
1. Veronese, FM. Biomaterials 22, 405 (2001).
2. Roberts, MJ. et al. Adv Drug Delivery Rev 54, 459 (2002).
3. Chapman, AP. Adv Drug Delivery Rev 54, 531 (2002).
4. DeFrees, S. et al. Glycobio 16, 833 (2006).
About AnaSpec, Eurogentec Group
AnaSpec, Eurogentec Group (anaspec.com) is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. As a subsidiary of Eurogentec, AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, oligonucleotides, and qPCRs. AnaSpec carries a broad product line of biochemicals and reagents for basic research, high-throughput screening and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008.