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Honolulu, HI, United States, 2006/08/17 - Researchers have developed a highly sensitive, optical bio-molecule sensor that can distinguish between bio-molecules based on the variation to the light intensity of light due to the change in the path of coupled input light..
The variation to the coupled light intensity and path is dependant on the nature of the bio-molecule and the density of the bio-molecules.
As the breadth of biosensor technology (silicon-chip based biomedical diagnostic technologies) continues to expand, there exists a growing need for improving the detection parameters, namely sensitivity, selectivity and speed of detection.
Dr. Shalini Prasad, Assistant Professor in the Department of Electrical and Computer Engineering at Portland State University, explains the background of his group's recent work to Nanowerk: "The biosample–device interface sets operational constraints on the various mechanical, material and preparatory aspects of how samples are collected, processed and applied to the device, as well as on establishing requirements for device biocompatibility. There are numerous approaches to high sensitivity biosensing, and these include a wide range of label-based techniques like fluorescent microarrays, as well as label-free methods such as surface plasmon resonance."
Read the full article on the Nanowerk website.
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By Michael Berger, Copyright 2006 Nanowerk LLC