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Thermo Fisher Scientific Develops New GC-MS Method to Comply with Federal Workplace Guidelines - Thermo Fisher Scientific Inc. introduces a new method for the confirmation of amphetamines in urine in accordance with recently updated United States Substance Abuse and Mental Health Services Administration Guidelines (NYSE: TMO)
Thermo Fisher Scientific Develops New GC-MS Method to Comply with Federal Workplace Guidelines

 

NewswireToday - /newswire/ - Holmes Chapel, Cheshire, United Kingdom, 2010/09/14 - Thermo Fisher Scientific Inc. introduces a new method for the confirmation of amphetamines in urine in accordance with recently updated United States Substance Abuse and Mental Health Services Administration Guidelines (NYSE: TMO).

   
 
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Thermo Fisher Scientific Inc., the world leader in serving science, introduces a new method for the confirmation of amphetamines in urine in accordance with recently updated United States Substance Abuse and Mental Health Services Administration (SAMHSA) Mandatory Guidelines for Federal Workplace Drug Testing Programs, implemented on the 1st May 2010. The recently launched Thermo Scientific ISQ single quadrupole gas chromatography-mass spectrometry (GC-MS) instrument can analyze a greater number of sympathomimetic amines in urine in line with these updated regulations. Further information on the new method is detailed in an application note, entitled “Analysis of an Expanded Panel of Sympathomimetic Amines in Urine using Single Quadrupole GC/MS”.

As part of the updated SAMHSA guidelines, multiple changes were made for the confirmation of amphetamine-class urine analysis. In addition to SAMHSA’s previously published guidelines for amphetamine and methamphetamine, three amphetamine-analog drugs were added to the panel, including 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyethylamphetamine (MDEA). The confirmatory cutoff concentration level for the regulated amphetamines has also been lowered from 500 ng/mL to 250 ng/mL. To enable its customers to comply with these changes, Thermo Fisher has developed a method for the confirmation and quantification of the extended sympathomimetic amine panel in human urine using the ISQ™ single quadrupole GC-MS. The method also complies with requirements outlined by the College of American Pathologists (CAP), the Society of Forensic Toxicologists (SOFT) and the European Workplace Drug Testing Society (EWDTS).

The new method offers broad linearity to cover a wide range of analyte concentrations, with R2 values of 0.9990 or higher for all analytes over the range of 25-25,000 ng/mL. It also offers excellent precision near the 250 ng/mL cutoff set out by SAMHSA and detection and quantification limits are set at 25 ng/mL, ensuring sensitive performance. Furthermore, the new method enables MDEA to elute at a retention time of less than five minutes, enabling increased productivity in high-throughput toxicology laboratories when confirming the five amphetamine-analog drugs now included in the revised SAMHSA guidelines.

The ISQ GC-MS is a highly robust and rugged system that provides high-throughput sample confirmatory analyses and 24/7 operation. The new ExtractaBrite™ removable ion source feature is designed to provide maximum uptime and productivity by extending the length of time between required source maintenance. As a result, the ISQ system offers simplified operation and maximum uptime for uninterrupted productivity across routine GC-MS applications including general forensics, forensic toxicology, food safety and environmental.

For more information on the new method and the Thermo Scientific ISQ single quadrupole GC-MS, please call +1 866 463 6522 or email analyze[.]thermofisher.com.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (thermofisher.com) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of more than $10 billion, we have approximately 35,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications.

 
 
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Thermo Fisher Scientific Develops New GC-MS Method to Comply with Federal Workplace Guidelines

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