The human monoclonal antibodies (mAbs) market is teeming with opportunities and was worth nearly $30 billion in 2009, growing at a healthy double digit rate of around 20 per cent. With an increasing number of mAbs attaining blockbuster status, pharmaceutical and biotech companies have been flocking to this market.
"In the competitive mAbs market, companies aim to be distinctive by developing enhanced technologies and processes," says Frost & Sullivan Industry Analyst Arun A. K. "Sorrento has constructed one of the largest mAbs libraries with industry-leading diversity, fully human and full-length mAbs that could be either commercialised or used for developing their own therapeutic candidates."
Another opportunity that has opened up for the Company is collaboration with leading industry participants. Since 2006 a number of deals were signed between a major pharmaceutical/biotech company and an antibody-centric biopharmaceutical company, illustrating the considerable opportunities for a proven mAb technology.
Sorrento Therapeutics has developed a ribonucleic acid (RNA) transcription-based amplification technology called STI Technology, which has competitive benefits over traditional PCR-based amplification methods for constructing antibody libraries. Unlike polymerase chain reaction (PCR), the STI Technology amplifies large numbers of different immunoglobulin variable domain sequences in parallel to generate human antibody libraries of vast diversity.
Sorrento Therapeutics also enables full mammalian display of mAbs and an efficient production system, thus, widens its commercial opportunities. Apart from these technical advantages, this technology can be easily adopted upon licensing without the Intellectual Property (IP)-related issues that are common with competing technologies.
"Further, Sorrento Therapeutics is taking great strides in enhancing its visibility," notes Arun. "It has hired an experienced business development professional from the antibody industry to promote and develop its business."
At present, the company is in talks with numerous enterprises to explore commercial opportunities. Besides this, it is committed to participating in major industry conferences to showcase and popularise its technology.
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About Sorrento Therapeutics
Sorrento Therapeutics, Inc. (sorrentotherapeutics.com) is a developmental stage biopharmaceutical company focused on discovery and development of human therapeutic antibodies for the treatment of a variety of disease conditions based on its proprietary technology platform. Established in 2006, Sorrento has invested in constructing human antibody libraries which will facilitate the rapid identification and isolation of highly specific mAbs for therapeutic purposes.
Sorrento Therapeutics Contact Information
Henry Ji, Ph.D., Chief Scientific Officer
Sorrento Therapeutics, Inc.
6042 Cornerstone Court West, Suite B
San Diego, CA 92121 U.S.A.
T: (858) 210-3701, F: (858) 210-3759
About Frost & Sullivan
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