NewswireToday - /newswire/ -
San Jose, CA, United States, 2009/07/09 - In response to the growing needs of the research community for zebrafish specific antibodies, peptides and other products, AnaSpec has launched the exciting new Z-Fish™ series of antibodies.
In response to the growing needs of the research community for zebrafish specific antibodies, peptides and other products, AnaSpec has launched the exciting new Z-Fish™ series of antibodies. Z-Fish™ antibodies are raised strictly from peptide antigens derived from zebrafish protein sequences, i.e. 100% zebrafish sequence homology. Leveraging AnaSpec’s expertise in peptide technology, the antigens used in raising these antibodies include non-phosphorylated and phosphorylated peptides. Z-Fish™ antibodies are provided in a 150 μl size, which is optimal for 15 mini gels.
Zebrafish has been used as a developmental model in elucidating the role of MMPs during embryogenesis/development. Zhang, J. et al. isolated and characterized zMMP-2 (which shows >80% identity and >90% similarity to its human counterpart);1 Yoong, et al, zMMP-9; 2 and Hildegass, JM. et al. zMMP-13 (52% identity with human or mouse);3 among others. AnaSpec is pleased to introduce a line of Z-Fish™ antibodies for MMP-2, 9, 11, 13, 14, 17 and 24. These antibodies were raised from sequences derived from the hinge region, internal or C-terminal sequence. They have been verified in ELISA and western blots using zebrafish lysates (see western blots below).
Soon-to-be-released Z-Fish™ antibodies include antibodies for MMP-18 (IN), MMP-18 (hinge), MMP-21 (IN), and MMP-28 (hinge).
1. Zhang, J. et al. Dev. Genes Evol. 213, 456 (2004).
2. Yoong, S. et al. Genes Expr. Patterns 7, 39 (2007).
3. Hillegass, JM. et al. Toxicol. Sci. 100, 168 (2007).
About AnaSpec, Inc.
AnaSpec (anaspec.com) is a leading provider of integrated proteomics solutions to the world’s largest biotech, pharmaceutical, and academic research institutions. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents, and combinatorial chemistry.