PRTODAY / NewswireToday Free press release distribution service network

Written by / Agency / Source: AnaSpec, Inc.

Check Ads Availability|e-mail Article


Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!

AnaSpec Introduces Fluorescent GO™ Peptides - Fluorescent peptides, peptides with a reporter fluorescent dye, are valuable probes used in visualizing intracellular processes and molecular interactions at the level of single cells
AnaSpec Introduces Fluorescent GO™ Peptides

 

NewswireToday - /newswire/ - San Jose, CA, United States, 2009/06/18 - Fluorescent peptides, peptides with a reporter fluorescent dye, are valuable probes used in visualizing intracellular processes and molecular interactions at the level of single cells.

   
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Fluorescent peptides, peptides with a reporter fluorescent dye, are valuable probes used in visualizing intracellular processes and molecular interactions at the level of single cells.1 The fluorescent dye can be attached to the amino (N) or carboxy (C)-terminus, or in the case of FRET (Fluorescence or Förster resonance energy transfer) peptides, the two dyes (donor and acceptor) can be at the amino and carboxy termini or in the internal peptide sequence.

Leveraging its dual expertise in peptides and fluorescent dyes, AnaSpec is pleased to offer a broad selection of fluorescently labeled peptides labeled with our proprietary HiLyte Fluor™ dyes, as well as classic dyes (FAM, FITC, TAMRA).

For use as enzyme activity detection probes
Peptide substrates used in detection of enzyme activity can contain either a single dye or in the case of FRET, two dyes. In the intact fluorescent substrates, there is low fluorescence prior to enzyme hydrolysis. Upon recognition of the substrate by a specific enzyme and subsequent cleavage, the quenched fluorescence is recovered. Increase in fluorescence is correlated to enzyme activity.2-3 AnaSpec’s single dye-labeled fluorescent peptide selection include substrates for kinases, caspases, cathepsins, HDAC (histone deacetylase), calpain, kallikrein, and others. Our FRET peptides, generally consisting of a dye (donor) and a non-fluorescent quencher (acceptor), include substrates for MMPs, Aggrecanase-1, HCV, HIV, cathepsins, renin, ACE2, α and β-secretases and others.

For use as targeting probes
Fluorescent peptides have been used in in vivo or in vitro studies for visualizing cellular processes and molecular interactions.1 In in vivo imaging, three-dimensional fluorescence images of the internal structures, especially of small animals, are produced. This technique requires the use of near infrared red (NIR) dyes since at higher wavelength, tissues do not absorb or scatter photons as strongly as when lower wavelength dyes are used.2-3 An example is an RGD peptide, c[RGDyK(HiLyte Fluor™ 750)], that AnaSpec synthesized for J. Rey of the Univ. of South Florida. This peptide was shown to bind preferentially to organs that are known to be rich in integrin avb3 (see poster for details). Another examples are the fluorescent cell penetrating peptides, FITC-LC-Antennapedia and TAMRA-labeled TAT (47-57), cat# 61211.

References:
1. Pap, EHW. et al. Exp. Cell Res. 265, 288 (2001).
2. Lakowicz, Joseph. Principles of Fluorescence Spectroscopy. New York: Springer, 2006.
3. Tung, C-H. Peptide Sci. 76, 391 (2004).

About AnaSpec

AnaSpec (anaspec.com) is a leading provider of integrated proteomics solutions to the world’s largest biotech, pharmaceutical, and academic research institutions. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents, and combinatorial chemistry.

 
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Written by / Agency / Source: AnaSpec, Inc.

 
 

Availability: All Regions (Including Int'l)

 

Traffic Booster: [/] Quick Newswire Today Visibility Checker

 

Distribution / Indexing: [+]

 
 
# # #
 

 
  Your Banner Ad showing on ALL
Pharma/BioTech/Nutrition articles,
CATCH Visitors via Your Competitors Announcements!


AnaSpec Introduces Fluorescent GO™ Peptides

Company website links NOT available to basic submissions
It is OK to republish and/or LINK any newswire for any legitimate media purpose as long as you name Newswire Today and LINK as the source.
 
  Is this your article?
Activate ALL web links and social stream by Upgrading to Press Release PREMIUM Plan Now!

|
Publisher Contact: Ping Yang 
408-452-5055 ping[.]anaspec.com
 
Newswire Today - PRZOOM / PRTODAY disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any AnaSpec, Inc. securities in any jurisdiction including any other companies listed or named in this release.

Pharma/BioTech/Nutrition via RSSAdd NewswireToday - PRZOOM Headline News to FeedBurner
Find who RetweetFollow @NewswireTODAY



Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!


Read Latest Articles From AnaSpec, Inc. / Company Profile


Read Pharma/BioTech/Nutrition Most Recent Related Newswires:

Frost & Sullivan Commends Nemaura for Developing Superior Transdermal Drug Delivery Technology Platforms, the Memspatch and Micropatch
Greenphire Sponsors Second Annual Clinical Trial Agreements, Investigator Payments and Fair Market Value Meeting
Genentech’s Gazyva Helped People with Previously Untreated Follicular Lymphoma Live Significantly Longer
BD Announces Adoption of Windows 10 ‘Internet of Things’ for the Pyxis™ ES System
Greenphire Named to Deloitte 2016 Technology Fast 500™
Genentech Showcases New Clinical Data Across a Variety of Blood Diseases at American Society of Hematology 2016 Annual Meeting
BD Collaborates with JDRF to Focus on Extended Wear Innovations for Insulin Infusion Delivery
BD Launches First Syringe Designed for Use with Humulin® R U-500 Insulin
MDxHealth Announces Unique CPT Code Awarded for ConfirmMDx from the American Medical Association
BD MAX™ Vaginal Panel Receives FDA Market Authorization to Detect Most Common Causes of Vaginal Infections
Greenphire Receives EU-US Privacy Shield Certification
The 2016 Georges Mathé Prize Recognizes Research on the Immunological Determinants of the Response to Breast Cancer Treatment
MDxHealth Announces Agreement with HIFU CLINIC Prostate Cancer Center for Distribution of SelectMDx in Poland
First Patient in Malaysia Receives TheraSphere™ Radioembolisation Therapy
FDA Approves Genentech’s Lucentis® (Ranibizumab Injection) Prefilled Syringe

Boost Your Social Network
& Crowdfunding Campaigns


LIFETIME SOCIAL MEDIA WALL
NewswireToday Celebrates 10 Years in Business


PREMIUM Members


Visit  La Bella Bakery Artisan Bakery Arizona

Visit  JobsWare.com





 
  ©2016 Newswire Today — Limelon Advertising, Co.
Home | About | Advertise/Pricing | Contact | Investors | Privacy/TOS | Sitemap | FRANCAIS
newswire, PR free press releases distribution service magazines engine news alert newsroom press room breaking news public relations articles company news alerts newswiredistribution ezine bizentrepreneur biznewstoday digital business report market search pr firms agencies reports distri-bution today investor relation successful internet entrepreneurs newswire distribution prtoday.com freenewswiredistribution asianewstoday bizwiretoday USA pr UK today - NOT affiliated with PRNewswire as we declined their partnership offer in 2013
 
PRTODAY & NewswireTODAY are NOT affiliated with USA TODAY (usatoday.com)