The Thermo Scientific Cellomics Comet v3.0 BioApplication technique enables rapid, automated assessment of DNA damage.
Thermo Fisher Scientific Inc., the world leader in serving science, will unveil the Thermo Scientific Cellomics Comet v3.0 BioApplication on booth #1663 at the SOT 48th Annual Meeting and ToxExpo, Baltimore, Maryland from March 15-19 2009. This unique new application uses a cell-based imaging approach for addressing the bottleneck of rapid and accurate DNA damage assessment based on the Comet assay. This assay, also known as Single Cell Gel Electrophoresis (SCGE) is a commonly used assay to ascertain DNA damage induced in cells by acute exposure to chemicals or radiation.
The Comet BioApplication runs on the industry-leading Thermo Scientific Cellomics ArrayScan VTI system (comprising instrumentation, informatics and reagent products) and provides automatic acquisition and quantification of Comet assays. Researchers are now able to rapidly test multiple compounds for the potential effects of DNA damage offering a more productive method for screening compounds earlier in the drug-discovery process. In addition the Comet BioApplication provides a more reproducible method for compound screening at substantially lower labor costs compared with traditional manual approaches to Comet quantification.
The Comet BioApplication for use on the Thermo Scientific Arrayscan VTI HCS Reader is a completely automated tool for acquiring and analyzing Comet assays to assess DNA damage in studies related to genotoxicity, ecotoxicity, and biomonitoring. With the launch of the new Cellomics Comet v3.0 BioApplication, more tests may be performed with an industry standard assay configuration. This automated, quantitative high content approach enables screening for indicators of genetic toxicity earlier in the development of therapeutic candidates and is designed to improve attrition rates, increasing efficiency and significantly reducing costs for pharmaceutical companies.
The Comet BioApplication, along with a selection of Thermo Scientific High Content products, can be seen at the Thermo Scientific product booth # 1663 Society of Toxicology (SOT) Annual Meeting and ToxExpo, Baltimore, Maryland, March 15-19 2009.
Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (thermo.com) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With annual revenues of $10.5 billion, we have more than 34,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. Thermo Scientific offers customers a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike.
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