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San Jose, CA, United States, 2008/10/07 - Thermo Fisher Scientific Inc., the world leader in serving science, today announced the availability of a method to detect melamine and cyanuric acid in food matrices.
The method uses Thermo Scientific instrumentation for liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) systems, and is published in the U.S. FDA's Laboratory Information Bulletin No. 4396, May 2007. Melamine is an industrial chemical used in the manufacturing of plastics, flame retardants and other products. Recent news coverage about the presence of melamine in infant formula, cookies and candy has once again raised public concern about the chemical in the food supply chain for both animals and humans. This latest finding comes roughly one year after the announced presence of melamine and cyanuric acid in pet food.
The LC-MS/MS method utilizes the Thermo Scientific TSQ Quantum triple quadrupole mass spectrometer coupled to a Thermo Scientific Surveyor MS pump and autosampler. Thermo Scientific Xcalibur data system software was used to acquire and analyze the data.
Thermo Fisher Scientific has also published a related application note (Thermo Scientific Application Note 424 - May 2008), "Analysis of Melamine and Cyanuric Acid in Food Matrices by LC-MS/MS." This application was developed on the TSQ Quantum Ultra in collaboration with the National Center for Food Safety and Technology at the Illinois Institute of Technology, Chicago, Illinois. Currently this method is being used as a reference by the labs under Administration of Quality Supervision, Inspection and Quarantine (AQSIQ) in China to develop an LC-MS/MS method using TSQ Quantum systems for the detection of melamine in milk and infant formula.
The Thermo Scientific TSQ Quantum triple quadrupole system is the only instrument that enables highly-selective reaction monitoring (H-SRM), which facilitates the quick and efficient analysis of complex samples such as food matrices and animal tissue. Additionally, the Thermo Scientific solution, when coupled to TurboFlow technology, has the advantage of providing a total solution from on-line sample preparation to data analysis, saving scientists and regulatory agencies valuable time.
Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With annual revenues of $10 billion, we have more than 30,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. Thermo Scientific offers customers a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike.
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