While protein electrophoresis is a well-established method in the field of protein expression analysis, the development of new techniques extending the principles of this technology has renewed interest in this experimental methodology.
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Protein electrophoresis is an efficient and relatively inexpensive method of analyzing the expression of proteins from biological samples. Innovative protein electrophoresis applications have created significant opportunities for market participants providing tools and products to life science researchers. The ubiquitous application of protein electrophoresis in research laboratories has driven market participants, both established and new, to focus on consistently improving the quality of tools provided to researchers. The migration to increase throughput technologies has also spurred the industry to develop higher throughput gel apparatus and automated imaging products that remove much of the labor and time required for analysis.
Although 2-D protein electrophoresis approaches may appear as simple extensions of 1-D techniques, the 2-D method is capable of providing information about global proteomic expression not available through many other methods. The separation of proteins along a second dimension provides greater resolution of cellular content, thereby aiding in the identification of proteins that may be identified as a biomarker that signals the presence of a diseased state. Additionally, the development of new non-chemiluminescent imaging modalities has not only helped drastically reduce the costs of 1-D experiments, but also provided high-throughput capabilities that researchers can use to study a greater number of targets.
“By building upon traditional 1-D approaches, novel 2-D protein electrophoresis have revived interest in protein expression analysis techniques,” notes Frost & Sullivan Research Analyst Shankar Sellappan, Ph.D. “The expanded capabilities of 2-D techniques and new signal analysis modalities for 1-D protein electrophoresis expects to aid in the growth of this market.”
Overall, the signal analysis products segment within the U.S. Protein Electrophoresis market expects a fare better outcome than that of apparatus or reagents. A great deal of innovation has occurred in this area with no competitive restrictions limiting the entry of new market participants. Signal analysis products enable scientists not only to analyze the information most effectively, but also to ask a greater number of questions.
“The simplicity and durability of protein electrophoresis products provide researchers with a solid platform on which to perform experiments. The large installed base of users ensures that protein electrophoresis will continue to play a prominent role in molecular biology experiments, with future growth likely to depend on the development of new approaches for signal analysis such as non-chemiluminescent based imaging. Techniques such as 2-D, that expand upon the fundamental principles of electrophoresis to provide additional sources of information, are also likely to generate growth opportunities,” cites Dr. Sellappan.
U.S. Protein Electrophoresis Markets, part of the Drug Discovery & Clinical Diagnostics Subscription, provides a comprehensive market forecast for the apparatus, reagents, and signal analysis products (hardware and software) used in protein electrophoresis. This forecast is based on the types of applications using these products, the saturation level among users, and new products that broaden the capabilities of this technology. Interviews with the press are available.
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