The $82 billion U.S. drug delivery market is showing no signs of saturation, with major patent expiries, generic competition, tightening Food and Drug Administration (FDA) regulations, and emerging drug delivery systems continuing to provide momentum. Among the 15 drug delivery systems surveyed by Frost & Sullivan, physicians prefer topical delivery, either as a transdermal patch or topical gel/cream, and expressed willingness to switch their current mode of therapy to one available in these forms.
A new end-user survey of more than 220 physicians and 650 patients by Frost & Sullivan, the Drug Delivery Technology: End-User Preferences, Utilization and Perceptions analysis (lifesciences.frost.com), finds that regardless of disease area, physicians select drug delivery methods that drive consistent patient compliance and effective outcomes. The survey traces usage patterns, analyzes preferences and opportunities among physicians and patients, and assesses their willingness to switch therapies based on the drug delivery method.
Drug Delivery Methods And Disease Types Covered
Delivery Method Disease - Type
Oral drug delivery - Type 1 diabetes
Nasal drug delivery - Type 2 diabetes
Transdermal drug delivery - Obesity
Topical drug delivery - Deep vein thrombosis
Subcutaneous injection (autoinjector) - Arterial thrombosis
Subcutaneous injection (prefilled syringe) - Atrial fibrillation/arrhythmia
Intramuscular injection (autoinjector) - Ischemic heart disease
Intramuscular injection (prefilled syringe) - Migraines
Intradermal injection - Multiple Sclerosis
Intravenous injection - ADHD
Intravenous infusion - Schizophrenia
Implantable infusion pump - Alzheimer’s disease
External infusion pump - Depression
Implant - Ulcerative colitis
Rectal drug delivery - Crohn’s disease, Psoriasis, Rheumatoid arthritis
For more information on this research, please email Britni Myers, Corporate Communications, at britni.myers[.]frost.com, with your full name, company name, job title, telephone number, company email address, company website, city, state and country.
The route of administration and drug delivery technology has a huge bearing on the adoption of, and compliance with, new as well as existing drugs. Among the surveyed physicians, only a quarter were considered early adopters of new drug delivery forms. Accordingly, manufacturers must listen to actual selection criteria and level of satisfaction data collected from end-users to find commercial success among medical practitioners.
"All things considered, physicians usually lean toward the treatment they feel will be most acceptable to their patients in order to ensure good compliance,” said Frost & Sullivan Vice President of Global Research Monali Patel Shastry.
These indicators are highly relevant in the current market scenario, wherein medication adherence is a growing concern, with momentous medical and economic consequences.
"When selecting the optimal drug delivery method, reimbursement incentives for improving adherence and impact on formulary decisions are proven to be important factors,” noted Frost & Sullivan Life Sciences Senior Industry Analyst Deborah Toscano. "Drug development pipelines are full of innovative drugs and biologics, and differentiation is increasingly important in this crowded market to gain and maintain market share.”
It is important to note the drivers of satisfaction and selection are not always the same across diseases and methods. For example, the several novel oral therapies for multiple sclerosis recently introduced offer significant advantages over the standard of care injectable therapies. However, more than 55 percent of physicians treating multiple sclerosis are likely to switch from the currently prescribed branded drug if the drug were available in a transdermal patch form, while 54 percent of the physicians treating migraines would prefer to switch to a drug using nasal administration.
This is in line with the 58 percent of multiple sclerosis patients willing to use a transdermal patch, and 50 percent of migraine patients willing to use a nasally administered drug. Further, 57 percent of physicians treating type 2 diabetes are most willing to switch from oral or injectable drugs to a topical treatment.
The Drug Delivery Technology: End-User Preferences, Utilization and Perceptions analysis is generated by Frost & Sullivan’s global Life Sciences practice. Related research includes: Analysis of the Global Type 2 Diabetes Therapeutics Market, United States Market for Rheumatoid Arthritis Pharmacotherapeutics, and Strategic Analysis of Anti-Obesity Prescription Drug Development. All research services included in subscriptions provide detailed market opportunities and industry trends evaluated following extensive interviews with market participants.
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Drug Delivery Technology: End-User Preferences, Utilization and Perceptions.