PRTODAY / NewswireToday Free press release distribution service network

More news: Nanotechnology
Written by / Agency / Source: Nanowerk, LLC

Check Ads Availability|e-mail Article


Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!

Molecular Imaging as a Step Towards Personalized Medicine - A new imaging technique allows detection of signals from molecules present at 10,000 times lower concentrations than conventional MRI techniques.
Molecular Imaging as a Step Towards Personalized Medicine

 

NewswireToday - /newswire/ - Honolulu, HI, United States, 2006/11/07 - A new imaging technique allows detection of signals from molecules present at 10,000 times lower concentrations than conventional MRI techniques..

   
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Nanotechnology Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Conventional diagnostic imaging is mainly based on morphological contrast that is a result of different general tissue characteristics. Molecular imaging is a new approach for detecting diseases much earlier, visualizing biological processes at the cellular and molecular level in living organisms, and detecting changes in biochemistry. Corresponding molecular markers appear in quite low concentrations. Hence, the imaging technique must be very sensitive. Magnetic resonance imaging (MRI) has some significant advantages in terms of using non-ionizing radiation (in contrast to x-rays) and giving high resolution tomographies for any arbitrary position and orientation. However, conventional MRI suffers from inherent low sensitivity. A new method, using xenon as the signal source, was developed by researchers in California and will make MRI an important technique in molecular imaging, offering a huge potential for specific detection of disease markers. The new technique allows detection of signals from molecules present at 10,000 times lower concentrations than conventional MRI techniques. Called HYPER-CEST, for hyperpolarized xenon chemical exchange saturation transfer, this new technique could become a valuable tool for medical diagnosis, including the early detection of cancer.

In vivo molecular imaging requires specific sensor molecules that exclusively target a biomolecule of interest. Such sensors are difficult to develop for MRI with sufficient sensitivity because the technique detects tiny magnetizations of molecules that are exposed to a magnetic field. There are many molecular imaging agents – MRI contrast agents, PET and SPECT probes, fluorescence probes like quantum dots – and there is already a huge variety of targeting groups used for these probes.
"The motivation for our work was to combine two clever detection methods to boost the MRI sensitivity" Leif Schröder explains to Nanowerk: "First, our xenon biosensor concept makes use of transferring the molecular information onto nuclei that are encapsulated in molecular cages and that can be detected at very low concentrations because they are hyperpolarized. This means that they have a much larger detectable magnetization. Second, we used an indirect detection assay that makes optimized use of all the xenon atoms. One biosensor molecule can be used to label thousands of xenon nuclei and to detect a significantly increased signal."

Schröder, a member of the Pines Lab at UC Berkeley, is first author of a recent paper, titled "Molecular Imaging Using a Targeted Magnetic Resonance Hyperpolarized Biosensor", that was published in the October 20, 2006 edition of Science.

The xenon biosensor project is a cooperation between the Pines Lab and the Wemmer Group at Lawrence Berkeley National Laboratory that started several years ago. The first paper on this biosensor concept was published in PNAS in 2001. Subsequently, several important steps towards the imaging application were presented, including work on optimized xenon delivery and the first one-dimensional imaging profiles.

Read the full article on the Nanowerk website.

About Nanowerk: Nanowerk is a leading nanotechnology information portal. Apart from its unique Nanomaterial Database™, with over 1,300 products from 90 suppliers, it provides the most complete nanotech events calendar; hundreds of links to universities, labs, researchers, associations, networks and international initiatives involved in nanotechnology; daily news; downloadable reports; and much more. The site includes a daily “Spotlight” section featuring Nanowerk-exclusive reviews and summaries of cutting-edge nanotechnology research by guest authors and Nanowerk editors. Nanowerk also publishes the nanoRISK newsletter – a constructive contribution to the debate about the potential risks of nanotechnology.

By Michael Berger, Copyright 2006 Nanowerk LLC

 
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Nanotechnology Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Written by / Agency / Source: Nanowerk, LLC

 
 

Availability: All Regions (Including Int'l)

 

Traffic Booster: [/] Quick Newswire Today Visibility Checker

 

Distribution / Indexing: [+]

 
 
# # #
 
 
  Your Banner Ad showing on ALL
Nanotechnology articles,
CATCH Visitors via Your Competitors Announcements!


Molecular Imaging as a Step Towards Personalized Medicine

Company website links NOT available to basic submissions
It is OK to republish and/or LINK any newswire for any legitimate media purpose as long as you name Newswire Today and LINK as the source.
 
  Is this your article?
Activate ALL web links and social stream by Upgrading to Press Release PREMIUM Plan Now!

|
Publisher Contact: Michael Berger - Nanowerk.com 
1-808-741-1739 michael[.]nanowerk.com
 
Newswire Today - PRZOOM / PRTODAY disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any Nanowerk, LLC securities in any jurisdiction including any other companies listed or named in this release.

Nanotechnology via RSSAdd NewswireToday - PRZOOM Headline News to FeedBurner
Find who RetweetFollow @NewswireTODAY



Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!


Read Latest Articles From Nanowerk, LLC / Company Profile


Read Nanotechnology Most Recent Related Newswires:

NEC Discovers 'Carbon Nanobrush' - The World's First Fibrous Aggregate of Carbon Nanohorns
Frost & Sullivan Commends RUSNANO for Accelerating the Russian Nanotechnology Industry with Its Unique Investment Strategy and Innovative Services
Imec and Crystal Solar Demonstrate 22.5 Percent nPERT Si Solar Cells on Kerfless Epitaxial Wafers
Nanomaterials for Printing Market Worth $1,974 Million by 2019 Reports MarketsAndMarkets
Nanotechnology in Medical Devices Market Worth $8.5 Billion by 2019 Finds MarketsandMarkets
Polymer Nanocomposites Market Worth $5,100 Million by 2020 Finds MarketsAndMarkets
First Speakers of EuroNanoForum 2015 Announced
OCSiAl Group Receives Frost & Sullivan Technology Innovation Award for its Game-Changing Carbon Nanotube Production Process
Elmo Features its NANO Ultra High Power Servo Drive at IAS 2014 in China
Carbodeon Ltd Oy Announces Improvements to Electroless Nickel Including A 3x Improvement in Wear Resistance
IMARC Group Publishes New Report Insights on Setting Up A Rare Earth Magnet Manufacturing Plant
Carbodeon Enables 20 Percent Increase in Polymer Thermal Filler Conductivity
Industry Veteran Fergus Clarke Joins Picodeon as CEO
Picodeon’s Pulsed Laser Deposition Technology Enables Microstructural Control
Imec Integrates CCD and CMOS Technology to Improve Performance of CMOS imagers

Boost Your Social Network
& Crowdfunding Campaigns


LIFETIME SOCIAL MEDIA WALL
NewswireToday Celebrates 10 Years in Business


PREMIUM Members


Visit  BizJobs.com

Visit  JobsWare.com





 
  ©2016 Newswire Today — Limelon Advertising, Co.
Home | About | Advertise/Pricing | Contact | Investors | Privacy/TOS | Sitemap | FRANCAIS
newswire, PR free press releases distribution service magazines engine news alert newsroom press room breaking news public relations articles company news alerts newswiredistribution ezine bizentrepreneur biznewstoday digital business report market search pr firms agencies reports distri-bution today investor relation successful internet entrepreneurs newswire distribution prtoday.com freenewswiredistribution asianewstoday bizwiretoday USA pr UK today - NOT affiliated with PRNewswire as we declined their partnership offer in 2013
 
PRTODAY & NewswireTODAY are NOT affiliated with USA TODAY (usatoday.com)